For the most part still surrounded by town walls dating back to the 16th century, the town of Cittā di Castello spreads out along the Tiber valley, on the spot where the Romans had founded the township of Tifernum Tiberinum.
Umbertide, which, in the area, is second in importance only to Cittā di Castello, was founded at around the 10th century according to the wishes of Uberto son of the King of Italy, and took the name of "Fracta filiorum Uberti".
Citerna, situated on a hill above the Cerfone and Sovara streams, is dedicated to agriculture even if in the last few years it has become a popular holiday resort.
The small town of Lisciano Niccone, which is to be found in the valley of the "Niccone" stream, nowadays has less than a thousand inhabitants, whose main activity is agriculture.
The town of Monte S. Maria Tiberina is situated in the valley of the Aggia stream, placed in a panoramic position which has made it become a popular holiday resort.
As with the major part of the towns in this zone which are not placed along the Tiber valley, Montone was founded on a hill in a beautiful panoramic position between two tributaries of the Tiber river: the Carpina and the Lana rivers.
Pietralunga town, which is situated in a controlling position in the Carpinella valley, was the seat of a Roman settlement because of its strategic placement. Its present aspect, surrounded by town walls and with its well-preserved strong-hold, is however, the result of urban developement during the Middle Ages.
Nowadays, San Giustino is a town of modern aspect whose main industries apart from agriculture,are the metal-working and nutritional industries.
