Famed for its mineral waters, Nocera Umbra is a town with a very old appearance which has sprung up along the valley of the Topino river.

Its buildings of major artistic value are without doubt the Cathedral and the church of St. Francis. The latter was built between the 14th and 15th centuries and is now the seat of the city's Pinacoteque, and contains, other than the splendid frescoes by Matteo of Gualdo, paintings by the Umbrian and Tuscan schools. In the Cathedral, which dates back to the 11th centuryand was reconstructed in the 15th century, the Romanic portal at the left-hand side and the maiolica pavement of the sacristy are noteworthy.